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Ligand · KTZ

KTZ · N4,N4-dimethyl-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

KTZ, N4,N4-dimethyl-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine (C20 H19 N5, 329.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
KTZ
Formula
C20 H19 N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

KTZ in 2 structures; the first of them:

  • 4CME · Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary… · KTZ A1270 · binds ARG14, SER95, ALA96, PHE97, ASP161, MET163, CYS168, TYR174 and 7 more
  • 4CME · Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary… · KTZ A1270 · binds ARG14, SER95, ALA96, PHE97, ASP161, MET163, CYS168, TYR174 and 7 more

Residues it binds most

MET 8, SER 8, LEU 8, ALA 8, ARG 8, ASP 8, GLY 8, PHE 8, PRO 8, TRP 8 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

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