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Ligand · KTN

KTN · Cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine

KTN, Cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine (C26 H28 Cl2 N4 O4, 531.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every…

Component
KTN
Formula
C26 H28 Cl2 N4 O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

KTN in 4 structures; the first of them:

  • 1JIN · P450eryF/ketoconazole · KTN A801 · binds SER58, SER59, ASP60, PRO61, PHE72, ALA74, TYR75, ASN89 and 11 more
  • 1JIP · P450eryF(A245S)/ketoconazole · KTN A801 · binds SER59, PRO61, PHE72, ALA74, TYR75, ASN89, GLY91, THR92 and 10 more
  • 1JIN · P450ERYF/KETOCONAZOLE · KTN A801 · binds SER58, SER59, ASP60, PRO61, PHE72, ALA74, TYR75, ASN89 and 11 more
  • 1JIP · P450ERYF(A245S)/KETOCONAZOLE · KTN A801 · binds SER59, PRO61, PHE72, ALA74, TYR75, ASN89, GLY91, THR92 and 10 more

Residues it binds most

LEU 4, ALA 4, SER 4, THR 4, ARG 4, ASN 4, CYS 4, GLY 4, PHE 4, PRO 4 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe

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