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Ligand · KSF

KSF · N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine

KSF, N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine (C18 H13 Cl N4, 320.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
KSF
Formula
C18 H13 Cl N4
Class
ligand
Structures
2
PDB entries
1

Binding sites

KSF in 2 structures; the first of them:

  • 2ZM1 · Crystal structure of imidazo pyrazin 1 bound to the kinase domain of human LCK… · KSF A513 · binds LEU251, GLY252, VAL259, ALA271, VAL272, LYS273, GLU288, MET292 and 11 more
  • 2ZM1 · Crystal structure of imidazo pyrazin 1 bound to the kinase domain of human lck… · KSF A513 · binds LEU251, GLY252, VAL259, ALA271, VAL272, LYS273, GLU288, MET292 and 11 more

Residues it binds most

VAL 2, ALA 2, GLU 2, GLY 2, LEU 2, MET 2, ASP 2, ILE 2, LYS 2, SER 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide

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