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Ligand · KSC

KSC · 7-[(cyclopropylmethyl)amino]-2-[(4-methoxyphenyl)amino]-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide

KSC, 7-[(cyclopropylmethyl)amino]-2-[(4-methoxyphenyl)amino]-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide (C19 H22 N6 O2, 366.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
KSC
Formula
C19 H22 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

KSC in 2 structures; the first of them:

  • 3AD6 · Crystal structure of Pyrazolo pyrimidine derivative bound to the kinase domain of human… · KSC A513 · binds LEU251, VAL259, ALA271, THR316, GLU317, TYR318, MET319, GLY322 and 4 more
  • 3AD6 · Crystal structure of pyrazolo pyrimidine derivative bound to the kinase domain of human… · KSC A513 · binds LEU251, VAL259, ALA271, THR316, GLU317, TYR318, MET319, GLY322 and 4 more

Residues it binds most

ALA 2, LEU 2, ASN 2, GLU 2, GLY 2, MET 2, SER 2, THR 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide

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