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Ligand · KQZ

KQZ · ~{N},~{N}-dimethyl-4-(1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine

KQZ, ~{N},~{N}-dimethyl-4-(1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine (C13 H13 N5, 239.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
KQZ
Formula
C13 H13 N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

KQZ in 2 structures; the first of them:

  • 6S1H · Crystal Structure of DYRK1A with small molecule inhibitor · KQZ A504 · binds ILE165, PHE170, VAL173, ALA186, LYS188, GLU203, VAL222, PHE238 and 6 more
  • 6S1H · Crystal structure of DYRK1A with small molecule inhibitor · KQZ A504 · binds ILE165, PHE170, VAL173, ALA186, LYS188, GLU203, VAL222, PHE238 and 6 more

Residues it binds most

VAL 2, GLU 2, LEU 2, PHE 2, ALA 2, ASP 2, ILE 2, LYS 2, MET 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

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