GL1X · GenesisL1 explorer

Ligand · KQK

KQK · ~{N},~{N}-dimethyl-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine

KQK, ~{N},~{N}-dimethyl-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine (C12 H12 N6, 240.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
KQK
Formula
C12 H12 N6
Class
ligand
Structures
2
PDB entries
1

Binding sites

KQK in 2 structures; the first of them:

  • 6S17 · Crystal Structure of DYRK1A with small molecule inhibitor · KQK A511 · binds ILE165, PHE170, VAL173, ALA186, LYS188, GLU203, VAL222, PHE238 and 7 more
  • 6S17 · Crystal structure of DYRK1A with small molecule inhibitor · KQK A511 · binds ILE165, PHE170, ALA186, LYS188, PHE238, GLU239, LEU241, LEU294 and 2 more

Residues it binds most

LEU 2, PHE 2, VAL 2, GLU 2, ALA 2, ASP 2, ILE 2, LYS 2, MET 1, SER 1 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.