GL1X · GenesisL1 explorer

Ligand · KNI

KNI · (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-({N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl}amino)-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide

KNI, (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-({N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl}amino)-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide (C33 H41 N5 O6 S2, 667.8 g/mol), in the MolNFT structures on GenesisL1: bound in 6…

Component
KNI
Formula
C33 H41 N5 O6 S2
Class
ligand
Structures
6
PDB entries
3

Binding sites

KNI in 6 structures; the first of them:

  • 1HPX · HIV-1 protease complexed with the inhibitor kni-272 · KNI B900 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP30, VAL32, ILE47 and 20 more
  • 2ZYE · Structure of HIV-1 Protease in Complex with Potent Inhibitor KNI-272 Determined by… · KNI B900 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 20 more
  • 3FX5 · Structure of HIV-1 Protease in Complex with Potent Inhibitor KNI-272 Determined by High… · KNI B900 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 20 more
  • 1HPX · HIV-1 protease complexed with the inhibitor kni-272 · KNI B900 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP30, VAL32, ILE47 and 20 more
  • 2ZYE · Structure of HIV-1 protease in complex with potent inhibitor kni-272 determined by… · KNI B900 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 20 more
  • 3FX5 · Structure of HIV-1 protease in complex with potent inhibitor kni-272 determined by high… · KNI B900 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 20 more

Residues it binds most

GLY 6, ILE 6, ASP 6, VAL 6, ALA 6, PRO 6, ARG 6, LEU 6, PHE 6 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.