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Ligand · KEJ

KEJ · N-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

KEJ, N-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (C18 H15 Cl N6 O2, 382.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
KEJ
Formula
C18 H15 Cl N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

KEJ in 2 structures; the first of them:

  • 6N77 · Structure of the human JAK1 kinase domain with compound 15 · KEJ A1201 · binds LEU881, GLY882, GLU883, GLY884, GLY887, LYS888, VAL889, ALA906 and 12 more
  • 6N77 · Structure of the human JAK1 kinase domain with compound 15 · KEJ A1201 · binds LEU881, GLY882, GLY884, GLY887, LYS888, VAL889, ALA906, MET956 and 9 more

Residues it binds most

GLY 4, LEU 4, GLU 4, VAL 4, LYS 4, ALA 4, ARG 4, ASP 4, MET 4, PHE 4 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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