Ligand · K8I
K8I · (2~{S},3~{R})-1-[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]-~{N}-methyl-~{N}-(3-methylphenyl)-3-oxidanyl-pyrrolidine-2-carboxamide
K8I, (2~{S},3~{R})-1-[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]-~{N}-methyl-~{N}-(3-methylphenyl)-3-oxidanyl-pyrrolidine-2-carboxamide (C21 H21 F3 N4 O2, 418.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB…
- Component
- K8I
- Formula
- C21 H21 F3 N4 O2
- Class
- ligand
- Structures
- 1
- PDB entries
- 1
Binding sites
K8I in 1 structure; the first of them:
- 7ZX1 · Crystal structure of Pol theta polymerase domain in complex with compound 22 · K8I AAA2603 · binds LEU2336, LEU2348, VAL2351, VAL2358, ILE2362, GLU2365, TRP2366, ILE2385 and 10 more
Residues it binds most
ILE 4, LEU 4, TYR 4, VAL 4, SER 4, CYS 4, GLU 4, MET 4, PHE 4, TRP 4 (residue and the binding sites it lines).
Found with
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