Ligand · K7U
K7U · 6-[3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl]-4-methylpyridin-2-amine
K7U, 6-[3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl]-4-methylpyridin-2-amine (C12 H13 F2 N3, 237.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the…
- Component
- K7U
- Formula
- C12 H13 F2 N3
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
K7U in 6 structures; the first of them:
- 7TS3 · Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in… · K7U A803 · binds GLN483, PRO570, VAL572, MET575, PHE589, SER590, GLY591, TRP592 and 5 more
- 7TSD · Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with… · K7U A805 · binds GLN478, PRO565, VAL567, PHE584, SER585, GLY586, TRP587, TYR588 and 4 more
- 7TSN · Structure of human endothelial nitric oxide synthase heme domain in complex with… · K7U A503 · binds SER246, GLN247, ARG250, PRO334, VAL336, ASN338, PHE353, SER354 and 5 more
- 7TS3 · Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in… · K7U A803 · binds GLN483, PRO570, VAL572, MET575, PHE589, SER590, GLY591, TRP592 and 5 more
- 7TSD · Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with… · K7U A805 · binds GLN478, PRO565, VAL567, PHE584, SER585, GLY586, TRP587, TYR588 and 4 more
- 7TSN · Structure of human endothelial nitric oxide synthase heme domain in complex with… · K7U A503 · binds SER246, GLN247, ARG250, PRO334, VAL336, PHE353, GLY355, TRP356 and 3 more
Residues it binds most
TRP 18, TYR 18, SER 16, MET 17, GLU 18, GLY 18, PHE 18, PRO 18, VAL 18, GLN 17 (residue and the binding sites it lines).
Found with
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