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Ligand · K7F

K7F · 4-[(4-{[4-(4-cyano-2,6-dimethylphenoxy)-5-(pyridin-4-yl)pyrimidin-2-yl]amino}piperidin-1-yl) methyl]benzamide

K7F, 4-[(4-{[4-(4-cyano-2,6-dimethylphenoxy)-5-(pyridin-4-yl)pyrimidin-2-yl]amino}piperidin-1-yl) methyl]benzamide (C31 H31 N7 O2, 533.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
K7F
Formula
C31 H31 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

K7F in 2 structures; the first of them:

  • 7KWU · Crystal Structure of HIV-1 RT in Complex with 16c (K07-15) · K7F A608 · binds PRO95, LEU100, LYS101, LYS103, LYS104, SER105, VAL106, VAL179 and 12 more
  • 7KWU · Crystal structure of HIV-1 rt in complex with 16C (K07-15) · K7F A608 · binds PRO95, LEU100, LYS101, LYS103, LYS104, SER105, VAL106, VAL179 and 12 more

Residues it binds most

LYS 2, PRO 2, TYR 2, LEU 2, VAL 2, GLU 2, HIS 2, ILE 2, PHE 2, SER 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

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