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Ligand · K0K

K0K · 2-[(3~{a}~{R},6~{R},8~{a}~{S})-1-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-6-ethyl-8-oxidanylidene-3,3~{a},6,8~{a}-tetrahydro-2~{H}-pyrrolo[2,3-c]azepin-7-yl]ethanoic acid

K0K, 2-[(3~{a}~{R},6~{R},8~{a}~{S})-1-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-6-ethyl-8-oxidanylidene-3,3~{a},6,8~{…

Component
K0K
Formula
C35 H42 Cl N5 O7
Class
ligand
Structures
2
PDB entries
1

Binding sites

K0K in 2 structures; the first of them:

  • 6RCF · ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-15]-OH · K0K A201 · binds MET14, TYR16, TRP23, LYS69, ASN71, ALA73, THR74, PHE77 and 5 more
  • 6RCF · Enah EVH1 in complex with ac-[2-cl-F]-[prom-2]-[prom-15]-oh · K0K A201 · binds MET14, TYR16, TRP23, LYS69, ASN71, ALA73, THR74, PHE77 and 5 more

Residues it binds most

ASN 2, TRP 2, ALA 2, ARG 2, GLN 2, LYS 2, MET 2, PHE 2, THR 2, TYR 2 (residue and the binding sites it lines).

Found with

  • NO3 · Nitrate ion

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