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Ligand · JZX

JZX · 5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine

JZX, 5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine (C21 H27 N7 O3 S2, 489.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
JZX
Formula
C21 H27 N7 O3 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

JZX in 2 structures; the first of them:

  • 3L16 · Discovery of (thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally… · JZX A1 · binds LYS802, VAL803, MET804, ALA805, TRP812, ILE831, LYS833, ASP836 and 13 more
  • 3L16 · Discovery of (thienopyrimidin-2-YL)AMINOPYRIMIDINES as potent, selective, and orally… · JZX A1 · binds LYS802, VAL803, MET804, ALA805, TRP812, ILE831, LYS833, ASP836 and 13 more

Residues it binds most

ILE 2, ASP 2, LYS 2, MET 2, VAL 2, ALA 2, GLU 2, LEU 2, PHE 2, THR 2 (residue and the binding sites it lines).

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