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Ligand · JXM

JXM · (8S)-9-[(2R)-2-hydroxy-2-phenylethyl]-2-(morpholin-4-yl)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one

JXM, (8S)-9-[(2R)-2-hydroxy-2-phenylethyl]-2-(morpholin-4-yl)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one (C20 H23 F3 N4 O3, 424.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
JXM
Formula
C20 H23 F3 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

JXM in 2 structures; the first of them:

  • 4UWH · Discovery of (2S)-8-((3R)-3-Methylmorpholin-4-yl)-1-(3-methyl-2-oxo… · JXM A1876 · binds PHE612, SER614, PRO618, ILE634, LYS636, ASP644, TYR670, MET682 and 10 more
  • 4UWH · Discovery of (2S)-8-((3R)-3-methylmorpholin-4-yl)-1-(3… · JXM A1876 · binds PHE612, SER614, PRO618, ILE634, LYS636, ASP644, TYR670, MET682 and 10 more

Residues it binds most

ASP 2, ILE 2, PHE 2, PRO 2, SER 2, GLN 2, LEU 2, LYS 2, MET 2, TYR 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion

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