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Ligand · JWY

JWY · N-{4-chloro-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl}-N'-phenylurea

JWY, N-{4-chloro-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl}-N'-phenylurea (C24 H21 Cl F N5 O2, 465.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
JWY
Formula
C24 H21 Cl F N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

JWY in 2 structures; the first of them:

  • 6MOB · Crystal structure of KIT1 in complex with DP2976 via co-crystallization · JWY A1015 · binds VAL603, ALA621, VAL622, LYS623, GLU640, LEU644, LEU647, VAL654 and 14 more
  • 6MOB · Crystal structure of KIT1 in complex with DP2976 via co- crystallization · JWY A1015 · binds VAL603, ALA621, VAL622, LYS623, GLU640, LEU644, LEU647, VAL654 and 14 more

Residues it binds most

LEU 2, VAL 2, ALA 2, CYS 2, GLU 2, ASP 2, GLY 2, HIS 2, ILE 2, LYS 2 (residue and the binding sites it lines).

Found with

  • NO3 · Nitrate ion

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