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Ligand · JW0

JW0 · (4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},12~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid

JW0, (4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},12~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid (C24 H41 O7 P…

Component
JW0
Formula
C24 H41 O7 P
Class
ligand
Structures
2
PDB entries
2

Binding sites

JW0 in 2 structures; the first of them:

  • 8K4S · CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P · JW0 E601 · binds ARG95, LYS96, VAL99, THR103, PHE107, PHE153, LEU156, GLU157 and 10 more
  • 8KEX · CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P, local · JW0 E601 · binds ARG82, ARG86, ARG95, LYS96, VAL99, THR103, PHE107, LEU156 and 10 more

Residues it binds most

LEU 2, PHE 2, ARG 2, TYR 2, GLY 2, VAL 2, ALA 2, ILE 2, LYS 2, PRO 2 (residue and the binding sites it lines).

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