GL1X · GenesisL1 explorer

Ligand · JS5

JS5 · (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-((2R,3R,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-diamino-2-((2S,3R,4R,5S,6R)-3-amino-4 ,5-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-hydroxycyclohexyloxy)-2-(hydroxymethyl)-4-(2-((R)-piperidi N-3-ylmethylamino)ethoxy)-tetrahydrofuran-3-yloxy)-tetrahydro-2H-pyran-3,4-diol

JS5, (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-((2R,3R,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-diamino-2-((2S,3R,4R,5S,6R)-3-amino-4…

Component
JS5
Formula
C31 H61 N7 O14
Class
ligand
Structures
2
PDB entries
1

Binding sites

JS5 in 2 structures; the first of them:

  • 2BE0 · Complex Between Paromomycin Derivative JS5-39 and the 16S-Rrna A-Site. · JS5 A50 · binds G12, U13, G14, A15, A16, G17, U18, C19 and 7 more
  • 2BE0 · Complex between paromomycin derivative JS5-39 and the 16S-rRNA a-site. · JS5 A50 · binds G12, U13, G14, A15, A16, G17, U18, C19 and 7 more

Residues it binds most

A 4, G 4, C 4, U 4 (residue and the binding sites it lines).

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