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Ligand · JQP

JQP · N-(3,5-dimethylphenyl)-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidin-2-amine

JQP, N-(3,5-dimethylphenyl)-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidin-2-amine (C26 H27 F N6, 442.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
JQP
Formula
C26 H27 F N6
Class
ligand
Structures
2
PDB entries
1

Binding sites

JQP in 2 structures; the first of them:

  • 6MH1 · CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH HU-10, A… · JQP A201 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, MET132 and 4 more
  • 6MH1 · Crystal structure of the first bromodomain of human BRD4 in complex with hu-10, a… · JQP A201 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, MET132 and 4 more

Residues it binds most

LEU 4, MET 4, TYR 4, ASN 4, CYS 4, ILE 4, PHE 4, PRO 4, TRP 4, VAL 4 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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