Ligand · JLK

JLK · (2~{R})-2-[[6-ethyl-5-(2-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoic acid

JLK, (2~{R})-2-[[6-ethyl-5-(2-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoic acid (C24 H23 N3 O2 S, 417.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component: JLK
Formula: C24 H23 N3 O2 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

JLK in 2 structures; the first of them:

6QZB · Structure of Mcl-1 in complex with compound 8d · JLK A401 · binds HIS224, ALA227, PHE228, MET231, VAL249, MET250, VAL253, PHE254 and 4 more
6QZB · Structure of mcl-1 in complex with compound 8D · JLK A401 · binds HIS224, PHE228, MET231, VAL249, VAL253, PHE254, ARG263, THR266 and 2 more

Residues it binds most

PHE 2, VAL 2, MET 2, ARG 2, HIS 2, LEU 2, THR 2, ALA 1 (residue and the binding sites it lines).

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