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Ligand · JL4

JL4 · 5-(2-methyl-1,3-thiazol-4-yl)thiophene-2-carboxylic acid

JL4, 5-(2-methyl-1,3-thiazol-4-yl)thiophene-2-carboxylic acid (C9 H7 N O2 S2, 225.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
JL4
Formula
C9 H7 N O2 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

JL4 in 2 structures; the first of them:

  • 5QEQ · PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with… · JL4 A401 · binds GLU2, MET235, ASP236, PRO241, SER242, ALA278, ILE281, MET282
  • 5QEQ · Pandda analysis group deposition -- crystal structure of PTP1B in complex with… · JL4 A401 · binds GLU2, MET235, PRO241, SER242, ALA278, ILE281, MET282

Residues it binds most

MET 2, ALA 2, GLU 2, ILE 2, PRO 2, SER 2, ASP 1 (residue and the binding sites it lines).

Found with

  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

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