Ligand · JIN

JIN · 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one

JIN, 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (C21 H15 Cl2 F N4 O, 429.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component: JIN
Formula: C21 H15 Cl2 F N4 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

JIN in 2 structures; the first of them:

2HZI · Abl kinase domain in complex with PD180970 · JIN A600 · binds LEU248, GLY249, TYR253, VAL256, ALA269, VAL270, LYS271, GLU286 and 14 more
2HZI · Abl kinase domain in complex with PD180970 · JIN A600 · binds LEU248, GLY249, TYR253, VAL256, ALA269, VAL270, LYS271, GLU286 and 14 more

Residues it binds most

VAL 4, ALA 4, GLU 4, GLY 4, LEU 4, MET 4, PHE 4, THR 4, TYR 4, ASP 4 (residue and the binding sites it lines).

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