Ligand · JG7

JG7 · (2S,4R)-4-[2-chloranyl-4-(4-ethylpiperazin-1-yl)phenyl]sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-(trifluoromethyl)cyclopropyl]carbonyl-pyrrolidine-2-carboxamide

JG7, (2S,4R)-4-[2-chloranyl-4-(4-ethylpiperazin-1-yl)phenyl]sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-(trifluoromethyl)cyclopropyl]carbonyl-pyrrolidine-2-carboxamide (C26 H33 Cl F3 N5 O4 S, 604.1 g/mol), in the MolNFT structures on…

Component: JG7
Formula: C26 H33 Cl F3 N5 O4 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

JG7 in 2 structures; the first of them:

4BS6 · Mouse cathepsin S with covalent ligand · JG7 A1342 · binds GLN141, GLY145, ALA146, CYS147, TRP148, LYS187, GLY190, GLY191 and 9 more
4BS6 · Mouse cathepsin S with covalent ligand · JG7 A1342 · binds GLN141, GLY145, ALA146, CYS147, TRP148, LYS187, GLY190, GLY191 and 9 more

Residues it binds most

GLY 4, TYR 4, ALA 4, ASN 4, CYS 4, GLN 4, HIS 4, LYS 4, MET 4, TRP 4 (residue and the binding sites it lines).

Found with

GOL · Glycerol

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