Ligand · JDP

JDP · 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide

JDP, 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide (C24 H23 N5 O2, 413.5 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every binding site with its…

Component: JDP
Formula: C24 H23 N5 O2
Class: ligand
Structures: 5
PDB entries: 3

Binding sites

JDP in 5 structures; the first of them:

7RLI · Cryo-EM structure of human p97 bound to CB-5083 and ADP. · JDP A901 · binds VAL474, ASP478, ILE479, GLY521, CYS522, GLY523, LEU526, SER652 and 8 more
7RLJ · Cryo-EM structure of human p97 bound to CB-5083 and ATPgS. · JDP A803 · binds VAL474, ASP478, ILE479, GLY521, CYS522, GLY523, LEU526, SER652 and 6 more
6MCK · P97 D1D2 with CB5083 bound · JDP A900 · binds VAL474, ASP478, ILE479, LEU482, CYS522, GLY523, LEU526, ALA655 and 7 more
7RLI · Cryo-EM structure of human P97 bound to cb-5083 and ADP. · JDP A901 · binds VAL474, ASP478, ILE479, GLY521, CYS522, GLY523, LEU526, SER652 and 8 more

Residues it binds most

GLY 60, ALA 60, ILE 60, LEU 60, ASP 60, CYS 60, THR 60, VAL 60, ARG 47, SER 41 (residue and the binding sites it lines).

Found with

ADP · Adenosine-5'-diphosphate
AGS · Phosphothiophosphoric acid-adenylate ester
MG · Magnesium ion

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