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Ligand · JAV

JAV · 4-fluoro-N'-[(3-hydroxyphenyl)sulfonyl]-5-methyl[1,1'-biphenyl]-3-carbohydrazide

JAV, 4-fluoro-N'-[(3-hydroxyphenyl)sulfonyl]-5-methyl[1,1'-biphenyl]-3-carbohydrazide (C20 H17 F N2 O4 S, 400.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
JAV
Formula
C20 H17 F N2 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

JAV in 2 structures; the first of them:

  • 6MAJ · HBO1 is required for the maintenance of leukaemia stem cells · JAV A704 · binds TRP350, PHE428, LEU429, ILE475, LEU476, THR477, TYR481, MET482 and 15 more
  • 6MAJ · HBO1 is required for the maintenance of leukaemia stem cells · JAV A704 · binds TRP350, PHE428, LEU429, ILE475, THR477, MET482, ARG483, GLN484 and 12 more

Residues it binds most

GLY 2, SER 2, TYR 2, LEU 2, ILE 2, ARG 2, GLN 2, GLU 2, LYS 2, MET 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • GOL · Glycerol

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