Ligand · J9U

J9U · (8~{R})-4-[2,4-bis(fluoranyl)phenyl]-8-methyl-7-[(2-methylpyrazol-3-yl)methyl]-6,8-dihydro-5~{H}-1,7-naphthyridine-2-carboxamide

J9U, (8~{R})-4-[2,4-bis(fluoranyl)phenyl]-8-methyl-7-[(2-methylpyrazol-3-yl)methyl]-6,8-dihydro-5~{H}-1,7-naphthyridine-2-carboxamide (C21 H21 F2 N5 O, 397.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component: J9U
Formula: C21 H21 F2 N5 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

J9U in 2 structures; the first of them:

7EPF · Crystal structure of mGlu2 bound to NAM597 · J9U A1202 · binds PHE623, LEU639, GLY640, PHE643, HIS723, ARG724, ASP725, MET728 and 11 more
7EPF · Crystal structure of MGLU2 bound to NAM597 · J9U A1202 · binds PHE623, LEU639, GLY640, PHE643, HIS723, ARG724, ASP725, MET728 and 11 more

Residues it binds most

PHE 2, SER 2, LEU 2, MET 2, ARG 2, ASN 2, ASP 2, GLY 2, HIS 2, ILE 2 (residue and the binding sites it lines).

Found with

FMN · Flavin mononucleotide

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