Ligand · J99
J99 · (10R)-7-amino-3-cyclopropyl-12-fluoro-1,10,16-trimethyl-16,17-dihydro-1H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one
J99, (10R)-7-amino-3-cyclopropyl-12-fluoro-1,10,16-trimethyl-16,17-dihydro-1H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one (C23 H24 F N5 O2, 421.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2…
- Component
- J99
- Formula
- C23 H24 F N5 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
J99 in 2 structures; the first of them:
- 4CTC · Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor… · J99 A2402 · binds LEU1122, GLY1123, VAL1130, ALA1148, LYS1150, VAL1180, LEU1196, GLU1197 and 11 more
- 4CTC · Structure of the human anaplastic lymphoma kinase in complex with the inhibitor… · J99 A2402 · binds LEU1122, GLY1123, VAL1130, ALA1148, LYS1150, VAL1180, LEU1196, GLU1197 and 11 more
Residues it binds most
LEU 2, GLY 2, ALA 2, ASP 2, VAL 2, ARG 2, ASN 2, CYS 2, GLU 2, LYS 2 (residue and the binding sites it lines).
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