Ligand · J82
J82 · 2-[2-(2-methyl-2,3-dihydro-indol-1-yl)-2-oxo-ethyl]-6-morpholin-4-yl-3H-pyrimidin-4-one
J82, 2-[2-(2-methyl-2,3-dihydro-indol-1-yl)-2-oxo-ethyl]-6-morpholin-4-yl-3H-pyrimidin-4-one (C19 H22 N4 O3, 354.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues…
- Component
- J82
- Formula
- C19 H22 N4 O3
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
J82 in 4 structures; the first of them:
- 4BFR · Discovery and Optimization of Pyrimidone Indoline Amide PI3Kbeta Inhibitors for the… · J82 A2000 · binds LYS771, TYR772, MET773, PRO779, LEU780, TRP781, ILE797, LYS799 and 11 more
- 4V0I · Water Network Determines Selectivity for a Series of Pyrimidone Indoline Amide PI3KBeta… · J82 A1500 · binds THR750, PHE751, MET752, PRO758, LEU759, TRP760, ILE777, LYS779 and 11 more
- 4BFR · Discovery and optimization of pyrimidone indoline amide PI3KBETA inhibitors for the… · J82 A2000 · binds LYS771, TYR772, MET773, PRO779, LEU780, TRP781, ILE797, LYS799 and 11 more
- 4V0I · Water network determines selectivity for a series of pyrimidone indoline amide PI3KBETA… · J82 A1500 · binds THR750, PHE751, MET752, PRO758, LEU759, TRP760, ILE777, LYS779 and 11 more
Residues it binds most
ILE 8, ASP 8, MET 8, VAL 8, LYS 8, PHE 8, TYR 8, GLU 8, LEU 8, PRO 8 (residue and the binding sites it lines).
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