GL1X · GenesisL1 explorer

Ligand · J5L

J5L · (3R,3aS,4R,6aR)-4-[2-(methylamino)-2-oxoethoxy]hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[(2Z)-2-(methylimino)-2,3-dihydro-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate

J5L, (3R,3aS,4R,6aR)-4-[2-(methylamino)-2-oxoethoxy]hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[(2Z)-2-(methylimino)-2,3-dihydro-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate (C32 H43 N5 O10 S…

Component
J5L
Formula
C32 H43 N5 O10 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

J5L in 2 structures; the first of them:

  • 5AHB · Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease… · J5L A1101 · binds ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, GLY48, GLY49 and 20 more
  • 5AHB · Disubstituted bis-thf moieties as new P2 ligands in non-peptidal HIV- 1 protease… · J5L A1101 · binds ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, GLY48, GLY49 and 20 more

Residues it binds most

ASP 2, GLY 2, VAL 2, ILE 2, ALA 2, THR 2, ARG 2, LEU 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.