GL1X · GenesisL1 explorer

Ligand · J43

J43 · 4-{[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin-4-yl]amino}benzenesulfonamide

J43, 4-{[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin-4-yl]amino}benzenesulfonamide (C12 H11 Cl N4 O3 S2, 358.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
J43
Formula
C12 H11 Cl N4 O3 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

J43 in 2 structures; the first of them:

  • 3MHO · Crystal structure of human carbonic anhydrase isozyme II with… · J43 A265 · binds TRP5, ASN62, HIS64, GLN92, HIS94, HIS96, GLU106, HIS119 and 11 more
  • 3MHO · Crystal structure of human carbonic anhydrase isozyme II with 4-[N-(6… · J43 A265 · binds TRP5, ASN62, HIS64, GLN92, HIS94, HIS96, GLU106, HIS119 and 11 more

Residues it binds most

HIS 2, VAL 2, PRO 2, THR 2, TRP 2, ASN 2, GLN 2, GLU 2, LEU 2, PHE 2 (residue and the binding sites it lines).

Found with

  • UNL · Unknown ligand
  • ZN · Zinc ion
  • DMS · Dimethyl sulfoxide

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.