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Ligand · J3A

J3A · 6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine

J3A, 6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine (C21 H25 N7, 375.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
J3A
Formula
C21 H25 N7
Class
ligand
Structures
2
PDB entries
1

Binding sites

J3A in 2 structures; the first of them:

  • 6EAS · Co-crystal of pseudokinase DRIK1 (drought responsive inactive kinase 1) bound to ENMD-2076 · J3A A501 · binds ILE232, GLY233, SER234, THR235, LEU240, ALA252, MET288, GLU307 and 7 more
  • 6EAS · Co-crystal of pseudokinase DRIK1 (drought responsive inactive kinase 1) bound to enmd-2076 · J3A A501 · binds ILE232, GLY233, SER234, THR235, LEU240, ALA252, MET288, GLU307 and 7 more

Residues it binds most

ALA 2, GLU 2, GLY 2, LEU 2, TYR 2, ILE 2, MET 2, PRO 2, SER 2, THR 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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