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Ligand · IZZ

IZZ · (2S)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol

IZZ, (2S)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol (C17 H21 N5 O, 311.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
IZZ
Formula
C17 H21 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

IZZ in 2 structures; the first of them:

  • 3F2N · Crystal Structure of Human Haspin with an Imidazo-pyridazine ligand · IZZ A800 · binds ILE490, GLY491, GLU492, VAL498, ALA509, ILE557, PHE605, GLU606 and 10 more
  • 3F2N · Crystal structure of human haspin with an imidazo-pyridazine ligand · IZZ A800 · binds ILE490, GLY491, GLU492, VAL498, ALA509, ILE557, PHE605, GLU606 and 10 more

Residues it binds most

GLY 2, ILE 2, ASP 2, GLU 2, PHE 2, ALA 2, ASN 2, LEU 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • PO4 · Phosphate ion
  • EDO · 1,2-ethanediol

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