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Ligand · IZ5

IZ5 · N-{(1S)-2-{4-[(5S)-1,1-dioxido-3-oxoisothiazolidin-5-yl]phenyl}-1-[4-(3-phenylpropyl)-1H-imidazol-2-yl]ethyl}-3-fluorobenzenesulfonamide

IZ5, N-{(1S)-2-{4-[(5S)-1,1-dioxido-3-oxoisothiazolidin-5-yl]phenyl}-1-[4-(3-phenylpropyl)-1H-imidazol-2-yl]ethyl}-3-fluorobenzenesulfonamide (C29 H29 F N4 O5 S2, 596.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
IZ5
Formula
C29 H29 F N4 O5 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

IZ5 in 2 structures; the first of them:

  • 2VEY · Crystal structure of protein tyrosine phosphatase 1B in complex with an… · IZ5 A1300 · binds TYR46, ARG47, ASP48, VAL49, ASP181, PHE182, GLY183, CYS215 and 10 more
  • 2VEY · Crystal structure of protein tyrosine phosphatase 1B in complex with an… · IZ5 A1300 · binds TYR46, ARG47, ASP48, VAL49, ASP181, PHE182, GLY183, CYS215 and 10 more

Residues it binds most

GLY 2, ARG 2, ASP 2, GLN 2, ALA 2, CYS 2, ILE 2, MET 2, PHE 2, SER 2 (residue and the binding sites it lines).

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