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Ligand · IZ1

IZ1 · N-[(1S)-2-{4-[(5S)-1,1-dioxido-3-oxoisothiazolidin-5-yl]phenyl}-1-(4-phenyl-1H-imidazol-2-yl)ethyl]-3-(trifluoromethyl)benzenesulfonamide

IZ1, N-[(1S)-2-{4-[(5S)-1,1-dioxido-3-oxoisothiazolidin-5-yl]phenyl}-1-(4-phenyl-1H-imidazol-2-yl)ethyl]-3-(trifluoromethyl)benzenesulfonamide (C27 H23 F3 N4 O5 S2, 604.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
IZ1
Formula
C27 H23 F3 N4 O5 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

IZ1 in 2 structures; the first of them:

  • 2VEU · Crystal structure of protein tyrosine phosphatase 1B in complex with an isothiazolidi… · IZ1 A1299 · binds TYR46, ARG47, ASP48, VAL49, ASP181, PHE182, GLY183, CYS215 and 8 more
  • 2VEU · Crystal structure of protein tyrosine phosphatase 1B in complex with an… · IZ1 A1299 · binds TYR46, ARG47, ASP48, VAL49, ASP181, PHE182, GLY183, CYS215 and 8 more

Residues it binds most

GLY 2, ARG 2, ASP 2, GLN 2, ALA 2, CYS 2, ILE 2, PHE 2, SER 2, TYR 2 (residue and the binding sites it lines).

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