IUB · (1S,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-2-{[N-({[(1R,2S)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucyl]amino}propane-1-sulfonic acid

Binding sites

IUB in 2 structures; the first of them:

• 7TQ8 · Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 14d · IUB A402 · binds HIS41, LEU49, TYR54, PHE143, LEU144, CYS145, GLY146, SER147 and 11 more
• 7TQ8 · Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 14D · IUB A402 · binds HIS41, LEU49, PHE143, LEU144, CYS145, GLY146, SER147, CYS148 and 10 more

Residues it binds most

HIS 2, CYS 2, GLN 2, LEU 2, ASP 2, GLU 2, GLY 2, LYS 2, MET 2, PHE 2 (residue and the binding sites it lines).

Found with

• IRK · (1R,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-2-{[N-({[(1R,2S)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucyl]amino}propane-1-sulfonic acid
• PG4 · Tetraethylene glycol