GL1X · GenesisL1 explorer

Ligand · IL2

IL2 · (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid

IL2, (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid (C22 H32 O4, 360.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries).…

Component
IL2
Formula
C22 H32 O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

IL2 in 4 structures; the first of them:

  • 3SP6 · Structural basis for iloprost as a dual PPARalpha/delta agonist · IL2 A901 · binds LEU247, ILE272, PHE273, CYS275, CYS276, GLN277, THR279, SER280 and 13 more
  • 3SP9 · Structural basis for iloprost as a dual PPARalpha/delta agonist · IL2 A901 · binds LEU219, VAL245, PHE246, ARG248, CYS249, GLN250, THR252, THR253 and 14 more
  • 3SP6 · Structural basis for iloprost as a dual PPARALPHA/DELTA agonist · IL2 A901 · binds LEU247, ILE272, PHE273, CYS275, CYS276, GLN277, THR279, SER280 and 13 more
  • 3SP9 · Structural basis for iloprost as a dual PPARALPHA/DELTA agonist · IL2 A901 · binds LEU219, VAL245, PHE246, ARG248, CYS249, GLN250, THR252, THR253 and 14 more

Residues it binds most

LEU 6, ILE 6, VAL 6, PHE 6, HIS 6, THR 6, CYS 6, TYR 6, GLN 6, MET 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.