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Ligand · IHR

IHR · ~{N}-cyclopropyl-3-methyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine

IHR, ~{N}-cyclopropyl-3-methyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine (C9 H11 N5, 189.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
IHR
Formula
C9 H11 N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

IHR in 2 structures; the first of them:

  • 7Z8W · Crystal structure of YTHDF2 with compound YLI_DC1_018 · IHR A602 · binds LYS416, SER417, TYR418, SER419, ASP422, TRP432, CYS433, SER434 and 4 more
  • 7Z8W · Crystal structure of YTHDF2 with compound YLI_DC1_018 · IHR A602 · binds LYS416, SER417, TYR418, SER419, ASP422, TRP432, CYS433, ASN462 and 2 more

Residues it binds most

TRP 4, SER 4, TYR 6, ASP 4, CYS 4, LYS 4, ASN 3, PHE 2, GLU 2, ILE 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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