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Ligand · IH6

IH6 · (3S)-4-{[4-(but-2-ynyloxy)phenyl]sulfonyl}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide

IH6, (3S)-4-{[4-(but-2-ynyloxy)phenyl]sulfonyl}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide (C17 H22 N2 O5 S2, 398.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
IH6
Formula
C17 H22 N2 O5 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

IH6 in 2 structures; the first of them:

  • 1ZXC · Crystal structure of catalytic domain of TNF-alpha converting enzyme (TACE) with inhibitor · IH6 A478 · binds GLY346, THR347, LEU348, GLY349, LEU350, GLU398, LEU401, VAL402 and 10 more
  • 1ZXC · Crystal structure of catalytic domain of TNF-alpha converting enzyme (tace) with inhibitor · IH6 A478 · binds GLY346, THR347, LEU348, GLY349, LEU350, GLU398, LEU401, VAL402 and 10 more

Residues it binds most

HIS 4, LEU 4, VAL 4, GLU 4, GLY 4, ALA 4, PRO 4, THR 4, TYR 4, ILE 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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