GL1X · GenesisL1 explorer

Ligand · IGC

IGC · N-[(1S,2R,3E)-1-({[alpha-D-galactopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]oxy}methyl)-2-H ydroxyheptadec-3-en-1-yl]octanamide

IGC, N-[(1S,2R,3E)-1-({[alpha-D-galactopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]oxy}methyl)-2-H ydroxyheptadec-3-en-1-yl]octanamide (C44 H81 N O18, 912.1 g/mol), in the MolNFT structures on GenesisL1: bound in…

Component
IGC
Formula
C44 H81 N O18
Class
ligand
Structures
2
PDB entries
1

Binding sites

IGC in 2 structures; the first of them:

  • 2Q7Y · Structure of the endogenous iNKT cell ligand iGb3 bound to mCD1d · IGC A601 · binds TYR73, SER76, PHE77, ARG79, ASP80, ILE81, LEU84, ILE98 and 14 more
  • 2Q7Y · Structure of the endogenous inkt cell ligand IGB3 bound to MCD1D · IGC A601 · binds TYR73, SER76, PHE77, ARG79, ASP80, ILE81, LEU84, ILE98 and 14 more

Residues it binds most

LEU 4, VAL 4, ILE 4, PHE 4, ASP 4, THR 4, TRP 4, SER 4, TYR 4, ARG 2 (residue and the binding sites it lines).

Found with

  • PLM · Palmitic acid
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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