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Ligand · ICF

ICF · 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether

ICF, 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether (C3 H2 Cl F5 O, 184.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
ICF
Formula
C3 H2 Cl F5 O
Class
ligand
Structures
4
PDB entries
2

Binding sites

ICF in 4 structures; the first of them:

  • 1XZ3 · Complex of apoferritin with isoflurane · ICF A201 · binds LEU24, SER27, TYR28, LEU81
  • 3F78 · Crystal structure of wild type LFA1 I domain complexed with isoflurane · ICF A1 · binds LEU132, VAL233, ILE235, TYR257, ILE259, LYS287, LEU298, GLU301 and 3 more
  • 1XZ3 · Complex of apoferritin with isoflurane · ICF A201 · binds LEU24, SER27, TYR28, LEU81
  • 3F78 · Crystal structure of wild type LFA1 I domain complexed with isoflurane · ICF A1 · binds LEU132, VAL233, ILE235, TYR257, ILE259, LYS287, LEU298, GLU301 and 3 more

Residues it binds most

LEU 6, TYR 6, ILE 4, LYS 4, GLU 4, VAL 4, PHE 2, SER 2 (residue and the binding sites it lines).

Found with

  • CD · Cadmium ion
  • MG · Magnesium ion
  • GOL · Glycerol

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