GL1X · GenesisL1 explorer

Ligand · I82

I82 · ~{N}-methyl-3-phenyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine

I82, ~{N}-methyl-3-phenyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine (C12 H11 N5, 225.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
I82
Formula
C12 H11 N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

I82 in 2 structures; the first of them:

  • 7YXE · Crystal structure of YTHDF2 with compound ZA_143 · I82 A601 · binds LYS416, SER417, TYR418, SER419, ASP422, TRP432, CYS433, SER434 and 5 more
  • 7YXE · Crystal structure of YTHDF2 with compound ZA_143 · I82 A601 · binds LYS416, SER417, TYR418, ASP422, TRP432, CYS433, SER434, ASN462 and 3 more

Residues it binds most

TRP 4, SER 4, ASP 4, ASN 4, CYS 4, LYS 4, TYR 4, THR 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.