Ligand · I6X
I6X · 5-{(1R)-3-amino-4-fluoro-1-[3-(5-prop-1-yn-1-ylpyridin-3-yl)phenyl]-1H-isoindol-1-yl}-1-ethyl-3-methylpyridin-2(1H)-one
I6X, 5-{(1R)-3-amino-4-fluoro-1-[3-(5-prop-1-yn-1-ylpyridin-3-yl)phenyl]-1H-isoindol-1-yl}-1-ethyl-3-methylpyridin-2(1H)-one (C30 H25 F N4 O, 476.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- I6X
- Formula
- C30 H25 F N4 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
I6X in 2 structures; the first of them:
- 4B00 · Design and Synthesis of BACE1 Inhibitors with In Vivo Brain Reduction of beta-Amyloid… · I6X A1507 · binds SER10, GLY11, GLN12, GLY13, LEU30, ASP32, GLY34, SER35 and 16 more
- 4B00 · Design and synthesis of BACE1 inhibitors with in vivo brain reduction of beta-amyloid… · I6X A1507 · binds SER10, GLY11, GLN12, GLY13, LEU30, ASP32, GLY34, SER35 and 16 more
Residues it binds most
GLY 2, SER 2, ASP 2, GLN 2, ILE 2, THR 2, TRP 2, ALA 2, ARG 2, ASN 2 (residue and the binding sites it lines).
Found with
- ACT · Acetate ion
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