Ligand · I67
I67 · N-{[4-({[3,5-dicyano-4-ethyl-6-(4-methyl-1,4-diazepan-1-yl)pyridin-2-yl]sulfanyl}methyl) phenyl]methyl}glycinamide
I67, N-{[4-({[3,5-dicyano-4-ethyl-6-(4-methyl-1,4-diazepan-1-yl)pyridin-2-yl]sulfanyl}methyl) phenyl]methyl}glycinamide (C25 H31 N7 O S, 477.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…
- Component
- I67
- Formula
- C25 H31 N7 O S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
I67 in 2 structures; the first of them:
- 7SFC · Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3735967A · I67 A1703 · binds ALA807, THR808, SER809, ASP810, PRO811, GLU856, ASP858, ARG1234 and 7 more
- 7SFC · Human DNMT1(729-1600) bound to zebularine-containing 12MER dsdna and inhibitor GSK3735967A · I67 A1703 · binds ALA807, THR808, SER809, GLU856, ASP858, ARG1234, PHE1235, ASN1236 and 4 more
Residues it binds most
DG 2, PHE 6, SER 4, ASP 4, GLU 4, TYR 4, ARG 2, GLN 4, TRP 4, CYS 3 (residue and the binding sites it lines).
Found with
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