GL1X · GenesisL1 explorer

Ligand · I2S

I2S · (7Z)-7-{[(4-chlorophenyl)methyl]imino}-1-(4-methylbenzene-1-sulfonyl)-3,4,5,7-tetrahydropyrrolo[4, 3,2-de]quinolin-8(1H)-one

I2S, (7Z)-7-{[(4-chlorophenyl)methyl]imino}-1-(4-methylbenzene-1-sulfonyl)-3,4,5,7-tetrahydropyrrolo[4, 3,2-de]quinolin-8(1H)-one (C24 H20 Cl N3 O3 S, 465.9 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry).…

Component
I2S
Formula
C24 H20 Cl N3 O3 S
Class
ligand
Structures
1
PDB entries
1

Binding sites

I2S in 1 structure; the first of them:

  • 7TFG · Structure of mouse double minute 2 homolog (MDM2) ring domain in complex with MA242 · I2S C501 · binds ASN433, THR455, HIS457, ARG444, THR463, LYS467, LEU487, TYR489 and 2 more

Residues it binds most

THR 1, ARG 1, ASN 1, HIS 1, LEU 1, LYS 1, PHE 1, PRO 1, TYR 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.