Ligand · I19
I19 · N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine
I19, N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine (C24 H30 F N7 O, 451.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…
- Component
- I19
- Formula
- C24 H30 F N7 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
I19 in 2 structures; the first of them:
- 2W17 · CDK2 in complex with the imidazole pyrimidine amide, compound (S)-8b · I19 A1300 · binds ILE10, GLY11, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 11 more
- 2W17 · CDK2 in complex with the imidazole pyrimidine amide, compound (S)-8B · I19 A1300 · binds ILE10, GLY11, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 11 more
Residues it binds most
LYS 2, ASP 2, GLN 2, LEU 2, PHE 2, VAL 2, ALA 2, ASN 2, GLU 2, GLY 2 (residue and the binding sites it lines).
Found with
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