Ligand · I14

I14 · N-(3-{[4-amino-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]ethynyl}-4-methylphenyl)acetamide

I14, N-(3-{[4-amino-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]ethynyl}-4-methylphenyl)acetamide (C20 H21 N5 O2, 363.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component: I14
Formula: C20 H21 N5 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

I14 in 2 structures; the first of them:

6WIW · c-Src Bound to ATP-Competitive Inhibitor I14 · I14 A601 · binds LEU273, VAL281, ALA293, ILE294, LYS295, GLU310, MET314, VAL323 and 11 more
6WIW · C-src bound to ATP-competitive inhibitor I14 · I14 A601 · binds LEU273, ALA293, ILE294, LYS295, GLU310, MET314, THR338, GLU339 and 7 more

Residues it binds most

ALA 4, GLU 4, LEU 4, MET 4, ILE 4, VAL 3, LYS 4, ASP 4, GLY 4, THR 4 (residue and the binding sites it lines).

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