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Ligand · I0O

I0O · 4-amino-4-deoxy-1-O-[(S)-hydroxy{[(2e,6e,10z,14z,18z, 22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy}phosphoryl]-alpha-L-arabinopyranose

I0O, 4-amino-4-deoxy-1-O-[(S)-hydroxy{[(2e,6e,10z,14z,18z, 22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy}phosphoryl]-alpha-L-arabinopyranose (C50 H84 N O7 P, 842.2 g/mol), in the…

Component
I0O
Formula
C50 H84 N O7 P
Class
ligand
Structures
4
PDB entries
2

Binding sites

I0O in 4 structures; the first of them:

  • 7TCG · BceAB nucleotide-free conformation · I0O A701 · binds TYR216, SER219, PHE223, MET237, ILE240, LEU241, VAL244, LEU302 and 7 more
  • 7TCH · BceAB E169Q variant ATP-bound conformation · I0O A701 · binds VAL47, LYS52, GLY53, ALA56, THR59, TYR216, SER219, LEU222 and 22 more
  • 7TCG · Bceab nucleotide-free conformation · I0O A701 · binds TYR216, SER219, PHE223, MET237, ILE240, LEU241, VAL244, LEU302 and 7 more
  • 7TCH · Bceab E169Q variant ATP-bound conformation · I0O A701 · binds LYS52, GLY53, ALA56, TYR216, SER219, PHE223, MET237, ILE240 and 14 more

Residues it binds most

LEU 4, GLY 4, ALA 4, PHE 4, VAL 4, ILE 4, SER 4, MET 4, TYR 4, HIS 3 (residue and the binding sites it lines).

Found with

  • ATP · Adenosine-5'-triphosphate

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