Ligand · HYZ
HYZ · N-[1-(3-fluorobenzyl)-1H-indazol-5-yl]-5-[(piperidin-1-ylamino)methyl]pyrimidine-4,6-diamine
HYZ, N-[1-(3-fluorobenzyl)-1H-indazol-5-yl]-5-[(piperidin-1-ylamino)methyl]pyrimidine-4,6-diamine (C24 H27 F N8, 446.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…
- Component
- HYZ
- Formula
- C24 H27 F N8
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
HYZ in 2 structures; the first of them:
- 2RGP · Structure of EGFR in complex with hydrazone, a potent dual inhibitor · HYZ A1 · binds LEU718, GLY719, VAL726, ALA743, LYS745, MET766, CYS775, ARG776 and 13 more
- 2RGP · Structure of EGFR in complex with hydrazone, a potent dual inhibitor · HYZ A1 · binds LEU718, GLY719, VAL726, ALA743, LYS745, MET766, CYS775, ARG776 and 13 more
Residues it binds most
LEU 2, ASP 2, GLY 2, MET 2, THR 2, ALA 2, ARG 2, CYS 2, GLN 2, LYS 2 (residue and the binding sites it lines).
Found with
- PO4 · Phosphate ion
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