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Ligand · HXL

HXL · 2-(4-(4-carbamimidoylphenoxy)phenyl)-1H-benzo[d]imidazole-6-carboximidamide

HXL, 2-(4-(4-carbamimidoylphenoxy)phenyl)-1H-benzo[d]imidazole-6-carboximidamide (C21 H18 N6 O, 370.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
HXL
Formula
C21 H18 N6 O
Class
ligand
Structures
4
PDB entries
2

Binding sites

HXL in 4 structures; the first of them:

  • 2FJV · RT29 Bound to D(CTTAATTCGAATTAAG) in complex with MMLV RT Catalytic Fragment · HXL G301 · binds DA4, DA5, DT6, DT7, DC8, DA10, DA11, DT12 and 3 more
  • 2FJX · RT29 bound to D(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment · HXL B301 · binds DG4, DA5, DA6, DT7, DG8, DA10, DT11, DT12 and 2 more
  • 2FJV · RT29 bound to D(CTTAATTCGAATTAAG) in complex with mmlv rt catalytic fragment · HXL G301 · binds DA4, DA5, DT6, DT7, DC8, DA10, DA11, DT12 and 3 more
  • 2FJX · RT29 bound to D(CTTGAATGCATTCAAG) in complex with mmlv rt catalytic fragment · HXL B301 · binds DG4, DA5, DA6, DT7, DG8, DA10, DT11, DT12 and 2 more

Residues it binds most

DA 4, DT 4, DC 4, DG 2 (residue and the binding sites it lines).

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