GL1X · GenesisL1 explorer

Ligand · HW0

HW0 · 6-{[(3R,4R)-4-{[5-(6-aminopyridin-2-yl)pentyl]oxy}pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine

HW0, 6-{[(3R,4R)-4-{[5-(6-aminopyridin-2-yl)pentyl]oxy}pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine (C21 H31 N5 O, 369.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…

Component
HW0
Formula
C21 H31 N5 O
Class
ligand
Structures
4
PDB entries
2

Binding sites

HW0 in 4 structures; the first of them:

  • 3UFW · Structure of rat nitric oxide synthase heme domain in complex with… · HW0 A800 · binds MET336, LEU337, ARG414, GLN478, PRO565, VAL567, PHE584, GLY586 and 7 more
  • 4CWX · Alpha-ketoglutarate-dependent dioxygenase COMPLEX1 · HW0 A800 · binds VAL106, LEU107, GLN249, PRO336, VAL338, ASN340, MET341, PHE355 and 7 more
  • 3UFW · Structure of rat nitric oxide synthase heme domain in complex with 6… · HW0 A800 · binds MET336, LEU337, ARG414, GLN478, PRO565, VAL567, PHE584, GLY586 and 7 more
  • 4CWX · Alpha-ketoglutarate-dependent dioxygenase COMPLEX1 · HW0 A800 · binds VAL106, LEU107, GLN249, PRO336, VAL338, ASN340, MET341, PHE355 and 7 more

Residues it binds most

TRP 8, MET 8, TYR 8, VAL 8, GLN 8, GLU 8, GLY 8, LEU 8, PHE 8, PRO 8 (residue and the binding sites it lines).

Found with

  • H4B · 5,6,7,8-tetrahydrobiopterin
  • HEM · Protoporphyrin IX containing Fe
  • ZN · Zinc ion
  • ACT · Acetate ion
  • CAS · S-(dimethylarsenic)cysteine

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.