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Ligand · HOZ

HOZ · (4S)-4,5-diaminopentanoic acid

HOZ, (4S)-4,5-diaminopentanoic acid (C5 H12 N2 O2, 132.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
HOZ
Formula
C5 H12 N2 O2
Class
ligand
Structures
8
PDB entries
4

Binding sites

HOZ in 8 structures; the first of them:

  • 2HOZ · Inter-subunit signaling in GSAM · HOZ A1 · binds GLU1147, GLY1162, SER1163, PRO1188, ASN1374, GLU1376, LYS1379
  • 2HP1 · Inter-subunit signaling in GSAM · HOZ B2 · binds GLY1094, TYR1301, ALA1303, GLY1304, THR1305, SER2029, VAL2031, ARG2032 and 4 more
  • 2HP2 · Inter-subunit signaling in GSAM · HOZ B2 · binds ALA1303, GLY1304, THR1305, SER2029, VAL2031, ARG2032, TRP2067, SER2163 and 4 more
  • 3USF · Crystal structure of DAVA-4 · HOZ A1 · binds SER1029, VAL1031, TRP1067, SER1163, ASN1217, MET1248, LYS1273, GLU1406 and 3 more
  • 2HOZ · Inter-subunit signaling in gsam · HOZ A1 · binds GLU1147, GLY1162, SER1163, PRO1188, ASN1374, GLU1376, LYS1379
  • 2HP1 · Inter-subunit signaling in gsam · HOZ B2 · binds GLY1094, TYR1301, ALA1303, GLY1304, THR1305, SER2029, VAL2031, ARG2032 and 4 more
  • 2HP2 · Inter-subunit signaling in gsam · HOZ B2 · binds ALA1303, GLY1304, THR1305, SER2029, VAL2031, ARG2032, TRP2067, SER2163 and 4 more
  • 3USF · Crystal structure of dava-4 · HOZ A1 · binds SER1029, VAL1031, TRP1067, SER1163, ASN1217, MET1248, LYS1273, GLU1406 and 3 more

Residues it binds most

SER 8, GLY 8, ASN 8, GLU 6, LYS 8, ALA 6, THR 6, TRP 6, VAL 6, ARG 4 (residue and the binding sites it lines).

Found with

  • PLP · Pyridoxal-5'-phosphate
  • EA5 · (4S)-4-amino-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid
  • KE4 · (4R)-5-amino-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid
  • PLR · (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate
  • PMP · 4'-deoxy-4'-aminopyridoxal-5'-phosphate

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